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Renee333
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06 Nov 2020, 7:41 pm

I was misdiagnosed Bipolar and I had tried to donate plasma at two different centers. I was banned from donating because I have antibodies. I had never had a blood transfusion so I didn't know how that could be. I read about antibodies that can pass from mother to baby through the placenta in some cases and cause ASD. Anyone know anything about this? Thanks.



Mountain Goat
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06 Nov 2020, 7:55 pm

It is a strange subject about the placenta because they say that the mothers and babies blood streams are totally seperate and that nothing can be passed through the blood, but at the same time they talk about smokers and drinkers effecting their childs blood stream which many say is faulse. It may alter their growth though.
I don't know myself either way. I just see that the medical professionals and the anti smoking and drinking movements are sending out different messages. Who is right?

I mention this as it maybe similar in a way because we were always taught in old medical books that the two blood streams are totally seperate.



rowan_nichol
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07 Nov 2020, 1:18 am

Mountain Goat wrote:
It is a strange subject about the placenta because they say that the mothers and babies blood streams are totally seperate and that nothing can be passed through the blood, but at the same time they talk about smokers and drinkers effecting their childs blood stream which many say is faulse. It may alter their growth though.
I don't know myself either way. I just see that the medical professionals and the anti smoking and drinking movements are sending out different messages. Who is right?

I mention this as it maybe similar in a way because we were always taught in old medical books that the two blood streams are totally seperate.


The placenta and the protein which makes it up are pretty cool things.
You are right in that it keeps the two blood streams separate, in that blood cells cannot pass through the placenta, which is a good thing as mother and baby would otherwise end up with their immune systems trating each other's blood cells as an infection, and things probably would not end well.

But, other things can pas through that protein layer. Nutrients, antibodies from the mother which will protect the baby for the first few months of life, oxygen can transfer from mother to baby and carbon dioxide from baby to mother.

Probably other stuff with molecules much smaller than blood cells can pass as well. An alcohol molecule, while bigger than an oxygen molecule is still pretty tiny compared to a blood cell.

I am left puzzled by the first post as to why the presence of antibodies would count against blood donation, and would really want to know which antibodies these would be.

If they were antibodies specific to a particular (and probably rather nasty) infection then declining the blood donation may be a reasonable precaution. There are some virus infections which are persistent, the virus infecting cells over a long term and though antibodies are produced and keep the virus in check for decades, its presence infecting cells, particularly blood cells means it would be very irresponsible to transfuse possibly infected cells into another person and spread the infection.



funeralxempire
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07 Nov 2020, 1:55 am

Renee333 wrote:
I was misdiagnosed Bipolar and I had tried to donate plasma at two different centers. I was banned from donating because I have antibodies. I had never had a blood transfusion so I didn't know how that could be. I read about antibodies that can pass from mother to baby through the placenta in some cases and cause ASD. Anyone know anything about this? Thanks.


Antibodies for? Mental illness isn't caused by an infection, so it wouldn't correlate with any antibodies in one's blood.


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Renee333
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08 Nov 2020, 12:04 am

I'm not sure exactly. All I know is that both plasma centers I had a false positive for syphilis but the confirmation test I don't have syphilis. I was asked if I have ever had a blood transfusion, which I haven't. So I have foreign antibodies that they said my body is used to but could harm anyone else so therefore I can't donate. I read something about MARS, a form of ASD. Which happens when the a certain antibody transfers through the placenta.



magz
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08 Nov 2020, 5:19 am

Moved the topic to Health, Fitness and Sport, as it seems more suitable there.


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jimmy m
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08 Nov 2020, 8:07 am

Generally if you have antibodies, then it means that you encountered some sort of sickness or disease and your body successfully fought it off and developed antibodies as your army of soldiers. So the root question is what did they detect? What form of illness did they find?

In medical terms "An antibody is a protein component of the immune system that circulates in the blood, recognizes foreign substances like bacteria and viruses, and neutralizes them. After exposure to a foreign substance, called an antigen, antibodies continue to circulate in the blood, providing protection against future exposures to that antigen."
Source: Antibody

Generally antibodies are detected from analysis of blood. So you said that you didn't have a transfusion, but did anyone take a sample of your blood?


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Renee333
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08 Nov 2020, 8:12 pm

Also certain antibodies do pass through the placenta I believe anti antibodies if the mother has autoimmune problems. As a matter of fact there's a name for it. MARS, it's a type of autism . A fetal brain barrier is porous and developing and some antiantibodies can damage brain development. They test plasma of course at the plasma center which is how I found out. Both times I was told it either had to be a transfusion or during childbirth.



Renee333
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08 Nov 2020, 8:27 pm

https://healthland.time.com/2013/07/09/ ... ism-cases/

This will explain better. I'ts pretty confusing to me.



Renee333
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08 Nov 2020, 8:32 pm

I don't know where I saw that it is called MARS ) :lol lmao!!
https://healthland.time.com/2013/07/09/ ... ism-cases/



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08 Nov 2020, 10:04 pm

Renee333 wrote:
I was misdiagnosed Bipolar and I had tried to donate plasma at two different centers. I was banned from donating because I have antibodies.


Antibodies to what exactly?
All of us have antibodies to many things.
Indeed people who are Rhesus factor negative who have been exposed to it and build antibodies are actually quite useful, their donated blood can be used to prevent haemolytic disease in newborn babies.