Not funny for me.
More like old news. Or stock knowledge. Or even common sense.
I just never assume anyone who seem to 'have it all' are all happy, happier overall or even content. Nor do have any underlying problems and vulnerabilities.
They only have it all more convenient in one or several fronts.
Depending on the individual; extroversion, as a behavior, can even be a coping mechanism.
Therefore, socializing, can be very much a form of addiction or distraction, just as much as any drug of choice do.
Also depending on the individual; social achievements and popularity, do not equally mean resonance with the crowd, or social fulfillment or even not feeling lonely.
Just do any achievements and terms of success in a person's context, it can be deemed meaningless or even a painful burden for themselves.
Therefore yes, being popular can cause depression.
Especially if the person in question don't want anything to do with it and is playing the stupid facades game in fear of losing face.