Come to think of it, there's a woman at my workplace like this as well - likely either depressed or an Aspie, or both.
The moment I saw her my first day at work, I developed a huge crush on her. However, I'm married, so I can only admire from afar, as it should be. She doesn't like me that way anyways, from what I can tell, so no worries there
She's exactly what I like -- Chinese-American, certain look to her, very pale skin, a certain kind of face, intelligent, well-read -- while some people think she's pretty, she's not at the top of anyone's list by far. She's also 35 and apparently not in a relationship, though she may have had one in the past with a guy whose pic and facebook responses seem to peg him as an Aspie (they apparently are not together). She does some Aspie things (like twisting), and comes off as cold, disinterested, or sour.
I think it's a shame -- to me, she's gorgeous, and she does have a great smile and some good humor when you get it out of her. I think she is probably overly picky, but also probably one who is hard to live with or around -- for instance, she lives with her sister right now after moving out here from another state, but she and her sister are not on great terms (there's an age gulf as well).
From what I can tell on her facebook page, she doesn't have a BF, doesn't seem to spend a lot of time with guys, just female friends, but isn't gay (her friends are homely but not lesbian or masculine). I do wish she was happy, and I still lust after her a bit too much (in my mind) when I'm around her, because she physically reminds me of several ex girlfriends and crushes.