I'm going to be honest. I can list more hardships women have in life than those men have in life. However, I'm going to refrain from stating that women have it harder for one reason.
Which list of hardships is more difficult to endure doesn't always come down to quantity, but the individual having to endure them.
If you are a shy man who lacks confidence and doesn't want to have to deal with the stress of financially supporting a family (if you want a family), and feel you would be happier in a more traditionally feminine role in life, then you might indeed find that women do have it easier, as they traditionally do not have to meet the expectations men do, that you struggle with.
If you are a woman who wants to be able to go about with the same freedoms men; travel to remote places alone without worrying about being raped or murdered by a serial killer, and have the same career opportunities men have. If you want people to really see you as an intellectual equal when you start talking about rebuilding your car engine, then you would probably find that it would be easier for you to cope with the list of difficulties men have.
It really does depend on what the individual can better tolerate. For those of you who find your list of difficulties absolutely unbearable, there is always the option of a sex change.
Of course you have to be aware that they can't completely feminize a masculine bone structure and they can't make a fully operational penis.
See? Everyone has their difficulties.