You sound like mostly young people, talking about clubs and such, so I'll give you my 20's answer.
I met my first husband when I was 19 and he is a VERY social person. So we went out, all the time, numerous times a week. It was fun sometimes, sometimes it was torture. He had many friends and a large family and his own business. He coached me continuously, and while good for me in retrospect, at the time it usually made me sad. He was much older, and I did not know I had AS. He felt I was young and inexperienced and he could teach me. He didn't know he was trying to socialize an Autistic person!
So I would try to remember all the stuff he would tell me to say and how to act. Then we'd get home and I'd get a lecture of everything I did wrong. "Why did you say 'that' to 'so n so'?" I never had a '100 A+' evening where I did not make any social faux pas.
The constant socializing was wearing, and I would be so tired and stressed that I couldn't get much done at home. It bothered me that my house wasn't clean enough (for me). There were other differences too, and he always thought his opinion was the right one. So I didn't have any input into my life. Not that he was mean, he just didn't understand why I would sometimes NOT want to have 20 people over for dinner, or even 2. I left him in my early 30's. But it was amicable.
My second husband is a geek, NT but not much for socializing. He enjoys having lunch with guys he works with, that he has something in common with. But he does not like dinner parties, or going to bars, or any parties really. Just me and him doing things nights and weekends. This is a much better relationship for me. More relaxing. After working all week I just need to stay in and rest up on the weekends so I can go back on Monday!
After the first marriage for a long time I never wanted to go to another party again. Now I find that I enjoy getting together with other women, for an evening of cards say, about once a month. But that's my limit.