I have never had many friends, and I think, after my schooldays, I lost interest in having them.
I have found that often, their 'caring' is rather shallow and it is actually quite rare if you end up with 1 or 2 who are genuine, and not fair weather types. That is my opinion.
Having said that, I am not that good with friendships as I tend to end up talking on about my current obsession, and asking how they are etc, doesn't seem to come naturally at all. I only have 1 rl friend and I only talk to them by phone. I have none online, that I would consider friends, having lost touch when I lost my interest in the game I talked to them on.
In rl, I tend to find I like to simply have 1 person I am close to, and that is usually a relationship.
When not in a relationship, I talk sometimes to elderly people who have known me a bit for some years, but I can go without social contact these days as well.
I don't know if I am depressed without it or not. I can find too much time with someone drives me nuts and leaves me wanting to escape.
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I am diagnosed as a human being.