Ranting ahead, fair warning.
God how I utterly despise that inquiry, it makes my blood boil with indignation and racks my mind with confusion. It's as sardonic and obnoxious as it is confusing and irrational. After 19 years of being alive I have yet to find a proper reply thereto and I don't believe I ever will... It's evolved over the years from shocked silence to a timid "hi" to gritting my teeth and mechanically rehearsing "Fine, how 'bout you?" but these are all equally awkward to me.
Beating a dead horse though it may seem, the question is asked without the slightest hint of sincerity or genuine inquisitiveness. It is almost never the case that whoever who asks "What's up?", "How are you?", "What's on your mind?" expects an honest or reasonable reply to such a question; making known one's true machinations is wholly inappropriate and even offensive in the context in which it's used, as is stating one's true mood or intentions when they're not salubrious and extroverted. God forbid a sincere reply to such an invasive question should ever escape your mouth instead of the pre-programed deception that we're so conditioned to concede at the utterance of that phrase, you would frighten the poor creature away with your honesty.
It is humiliating and disingenuous in the sense that it defeats choice preemptively and sets itself up to ensnare you in a pitfall of conformity. What I mean by that is - The only appropriate answer to that question to he who asks is some variant of:
I'm fine, how 'bout you?
I'm great, thanks for asking
Good
Or the least banal:
Nothin'
Is any rational human being - let alone an Aspie, ever truly contented with such a sweeping statement? In the case of the first three it's hardly ever so simple, and in the case of the last, absolute rubbish! None of these replies are organic: None of them reflect one's inner toils or passions and overshadow the profound musings of one's heart with a cloak of vanity. They defeat the possibility of further elaboration with their dishonesty. It is a verbal contract, given against the consent of its signatories, to which one must acquiesce their rights to a profound or interesting conversation before being allowed to proceed with the inevitable drivel we call "Small talk".
"But shyteddy", you quip, "A stranger has no interest in knowing such things about somebody they've never met or know anything about". To which I say that is precisely my point ~ The only time it's appropriate, to my senses, to use "What's up?" or any of its derivatives is when you really want to explore the depths of someone's heart. When you're ready to hear an ugly, saddening, intriguing, breathtaking, possibly banal, or highly complex answer to the question (because in real life there's hardly an ever optimistic and unthinking person), or when you're ready to discuss life in depth and get to know somebody on an intimate level - then ask them, by all means, how they are, then brace yourself, because the depth of ones humanity cannot be summarized in a single sentence. But asking the question in casual conversation is irrational and bizarre to me. It's like asking somebody "How's your gall bladder?" as a conversation starter, I don't understand how this saying ever seeped its way into our everyday vernacular or why its ubiquitously used as a greeting across many cultures and languages, but if I did, I suppose I wouldn't be an Aspie on Wrongplanet... Anywho, that's why I hate the phrase "what's up?". I hope that I'm not alone in this sentiment.