It depends on the anime and its genre.
Shoujo series (aimed at girls) are far less likely to have female characters with a massive bust than shounen series (aimed at lads). If a woman does have a large bust in a shoujo work, there doesn't seem to be as much attention drawn to it as there would in a comedy shounen work.
A lot of the time, mangaka and anime artists draw characters with humongous, Super Sonico-like boobs for fanservice reasons, hence why the trope is particularly popular in ecchi series and other series aimed at guys who like girls. However, in many series, it's not always the case where girls either have no bust or a huge bust.
One example is a franchise I'm into (Love Live) where the breast size among the girls varies a bit. Most of the girls have noticeable but average-looking breasts, while some are more well-endowed, and some have a smaller chest.
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I'm sailing across Spectrum Sea, in my little boat.
The waters of the port were choppy. After I set off, there was a long, massive storm.
Years later, however, the sea calmed. I'm still on tranquil sea, but I'll never reach the Neurotypical Beach.