Mendel, the founder of genetics, Garcia Marquez, the author of One Hundred Years of Solitude, and ConcernedApe, the maker of Stardew Valley, are three good examples. They have made great achievements in the fields of biology, literature, and games respectively , without establishing connections with people.
But I don’t encourage you to cut ties with people. There are certainly a few examples of success, but there are countless examples of failure. I hope you will think twice before you act.
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For I so loved the world, that I gave My theory and method, that whosoever believeth in Me should not be oppressed, but have a liberated life. /sarc