Are we at the edge of another pandemic? H5N1

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jimmy m
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27 Mar 2025, 10:26 am

On 27 June 2024, 9:49 A.M., I summarized the approach to survive a very deadly disease called H5N1 Avian Flu, Highly Pathogenic Avian Influenza. I have covered a lot of information over the past several weeks on the next potential pandemic called H5N1. I have come to realize this pandemic will primarily be transmitted by insects, primarily Mosquitoes. Mosquitoes infect humans with a blood to blood transfer between infected to uninfected birds/animals/humans.

There’s a saying that those who do not learn from history are doomed to repeat it.

H5N1 has spread across many types of birds dealing wave after wave of deaths. In the last few years, it has infected over 500 different species of birds, driving some to near extinction. This virus has established its presence in 108 countries, across five continents. It even transitioned to chickens. But it is on the move and has impacted many types of animals, most recently dairy cattle. It has spread to 70 mammal species globally. It is in our homes (cats and mice). During the beginning of 2025, bird flu made the transition to sheep in the U.K. It is on the move and another species is contracting this threat. It is beginning to show up in pigs as a very deadly Swine Flu. -- Pigs are a "mixing vessels" for influenza viruses, specifically those infecting birds, humans, and other pigs. If H5N1 were to become endemic in U.S. pigs, then those viruses could undergo genetic reassortment, creating entirely novel strains, very deadly human strains.

This virus has been evolving over the past few years. It began with birds and spread to animals and humans. The disease is passing across a maze of viruses in recent years including H5N1, H5N2, H5N3, H5N5, H5N6, H5N8 and H5N9. But in my opinion the primary threat is H1N1.

H1N1 decimated the human population during the First World War. It went by many names including the Spanish Flu which killed between 50 and 100 million people during the period from 1918-1919. This plague went by many names. The Americans fell ill with "three-day fever" or "purple death." The French caught "purulent bronchitis." The Italians suffered "sand fly fever." German hospitals filled with victims of Blitzkatarrh or "Flanders fever. Sand fly fever is an arthropod-borne viral disease, also known as “Phlebotomus fever”, “mosquito fever”.

From 1918 to 1919, the Spanish flu infected an estimated 500 million people globally. This amounted to about 33% of the world's population at the time. In addition, the Spanish flu killed about 50 million people, about 6 percent of the Earth's population. Since the world population has grown around 5 times in the last 100 years. The threat might impact 2.5 billion people should it materialize today.


https://www.youtube.com/watch?v=RVpBFy_TRtA

How were the victims of H1N1 treated in front line hospitals during 1918/1919? No matter what they called it, the virus attacked everyone similarly. It started like any other influenza case, with a sore throat, chills and fever. Then came the deadly twist: the virus ravaged its victim's lungs. Sometimes within hours, patients succumbed to complete respiratory failure. Autopsies showed hard, red lungs drenched in fluid. A microscopic look at diseased lung tissue revealed that the alveoli, the lungs' normally air-filled cells, were so full of fluid that victims literally drowned. The slow suffocation began when patients presented with a unique symptom: mahogany spots over their cheekbones. Within hours these patients turned a bluish-black hue indicative of cyanosis, or lack of oxygen. When triaging scores of new patients, nurses often looked at the patients' feet first. Those with black feet were considered beyond help and were carted off to die.

In my humble opinion, these diseases are transmitted by insects. An insect bites an infected bird/animal/human and then transmitted the blood directly to another bird/ animal/human. The following is a good approach to limiting the spread in humans.

1. You can protect yourself from mosquito bites in two ways. If you spend a lot of time outdoors you can create protective clothing (boots, clothing and camping gear) that repel mosquitoes by treating them with Permethrin.

2. You can also protect yourself from mosquito bites by applying mosquito repellent on you skin. This will provide short protection (several hours) to drive away mosquitoes. There are a variety of products available. They include DEET, Picaridin, IR3535, Oil of lemon, Para-menthane-diol eucalyptus, and 2-Undecanone.

3. Another product that can help prevent mosquito bites is Metofluthrin. Metofluthrin is a pyrethroid used as an insect repellent. The vapors of metofluthrin are highly effective and capable of repelling up to 97% of mosquitoes in field tests. Metofluthrin is used in a variety of consumer products, called emanators, for indoor and outdoor use. These products produce a vapor that protects an individual or area. Effectiveness is reduced by air movement. Metofluthrin is neurotoxic, and is not meant to be applied directly to human skin.

4. Accidents can happen. What to do immediately after being bitten by a mosquito? Treat the bite with Tecnu Topical Analgesic Anti-Itch Spray (Diphenhydramine HCl 2%). There is another product that can diminish the effects of being bitten by an infected insect. It is called ChiggereX. This product contains 10% Benzocaine.

5. If you become infected with H5N1 treat the condition immediately using one of four FDA-approved antivirals for influenza: (1) Baloxavir (Xofluza), (2) Zanamivir (Relenza), (3) Peramivir (Rapivab). These are prescription drugs and will require a doctors prescription. Time is of the essence here. This condition will begin to destroy the human body and make it impossible to treat within a few days. Time is of the essence.

The latest research has shown that another drug called Oseltamivir phosphate (Tamiflu) is ineffective in treating this disease in recent cases in both humans and chickens.

6. Some people are very vulnerable to mosquito bites. These are people with open wounds. Just covering the wounded area with bandages will not protect you. Mosquitoes can smell your blood and you become a prime target. I suffered a small bleed and was attacked by around 50 mosquitoes in less then two hours outdoors. (Luckily I had protected myself with DEET before I went outside and as a result, NOT ONE MOSQUITO WAS ABLE TO BITE ME.) This may also be a problem for women who are going through their menstrual period.

7. Go on the offensive. Wage a war on mosquitoes. In general, mosquitoes live in a hot humid environment. They most commonly infest Ponds, Marshes, Swamps, and Other wetland habitats. So minimize their breeding grounds. Wage war on mosquitoes.

8. Use our friends. What, you didn't realize we have allies in our war on Mosquitoes? We have many friends. Some are birds like woodpeckers, some are other insects like dragonflies, some are fish like gambusia affinis.

9. Wastewater tracking of H5N1 can identify the specific regions in the U.S. where the outbreak is underway. One of these regions is San Francisco, California. This area could be Ground Zero of the outbreak. But we cannot monitor the threat because the funding for Wastewater tracking has been halted. But time has been wasted and H5N1 is on the move and Central Valley in California is in the epicenter.

10. Vaccinations may provide protection from a very deadly form of H5N1. A neutralizing antibody bnAb called MEDI8852, which was discovered and developed by Medimmune, now part of AstraZeneca. MEDI8852 targets a portion of a key flu protein that is less prone to change than other parts of the virus and thus is capable of conferring protection against a wide range of flu viruses. This vaccination was tested on Macaque, a species (with almost human qualities), and this vaccine provided a remarkable and measurable cure.

In the historic past, migrating birds were the long distance transport agents of Highly Pathogenic Avian Influenza H5N1. Seasonally they would move the infectious disease between the northern and southern hemispheres as the seasons changed from summer to winter. But now as humans have developed means of rapid transport, such as jet aircraft, the speed and distance this virus can spread is rapidly accelerated.


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jimmy m
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27 Mar 2025, 12:06 pm

A recent report out of China describes a new variant of H5N1 that has become more deadly to humans.

China Centers for Disease Control and Prevention reports on the dynamics of H5N1 variants and the response measures of primary and secondary schools in Beijing and Shanghai
An internal document titled "National Center for Disease Control and Prevention reports on the dynamics of H5N1 variants and analysis of response measures of primary and secondary schools in Beijing and Shanghai." The data disclosed that "as of 6:36 on March 13, 2025, the H5N1 variant (tentatively named A/H5N1-2025E) has a new mutation in the hemagglutinin (HA) protein gene. Animal experiments have shown that its ability to bind to mammalian cells has increased, and the risk of human-to-human transmission has increased from low to medium."

The data also showed that "detection distribution: As of March 12, a total of 127 positive samples were reported nationwide, of which 68% were samples from live poultry market environments, and 25% were asymptomatic carriers among poultry workers. Sporadic cases were concentrated in the densely populated breeding areas of the Yangtze River Delta and the Pearl River Delta."

The secretive CCP in China is currently tracking the following regions for this exploding outbreak: Xitiangezhuang, Shilibao, Taishitun, Xinchengzi, Shicheng, Xiwengzhuang, Dongshaoqu, Dachengzi, Mujiayu, and Gubeikou.


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jimmy m
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28 Mar 2025, 8:27 am

China is hiding secrets from the world. They are at the epicenter of H5N1 pandemic.
This pandemic is occurring in China but the CCP leadership is keeping it silent.

I wrote about this on 04 Mar 2025, 10:06 am in this thread.

Hiding Secrets in Plain Sight.

Something came to mind about a major pandemic in China near the end of 2023. It was killing hundreds of thousands, perhaps millions of children in China at the time. Their bodies were cremated and the deaths were hidden from the world. At the time Chinese people began to seek information as they panicked. I recorded the information here on Wrong Planet.

Is this Round 2 of a new Pandemic?

Their bodies were cremated. As a result of this pandemic, China made significant changes. They went from a draconian mask rule that was very depressive and enforced into an open rule of throw away the masks. They also implemented another change. They had a ONE CHILD RULE. This limited the number of babies a mother could produce. They changed this to a THREE CHILD RULE and began encouraging mothers to have several babies.

So what do I think might be happening? H5N1 is on the move in the U.S. Many people in the past couple years have gotten H5N1 but their conditions have been mild. A very small number have experienced a very severe variant with a very high death rate in humans. But this condition may evolve into an extremely deadly adult version of H1N1.


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jimmy m
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28 Mar 2025, 9:41 am



According to this article:
Severe cases can lead to bronchitis or pneumonia (mycoplasma pneumonia).
Children's hospitals are also facing strain with rising pneumonia and "white lung" cases reported.


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ASPartOfMe
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28 Mar 2025, 6:03 pm

Egg prices plunging as bird flu subsides and shortages dissipate

Quote:

Egg prices are suddenly plunging as the bird flu begins to wane and imports surge to fill the gap.

Why it matters: A massive outbreak of avian influenza has wiped out more than 166 million chickens since 2022, leading to sporadic egg shortages and price hikes.

It's also turned into a political issue with Republicans and Democrats arguing about who's to blame — and President Trump taking credit for the decline in prices in recent weeks.

By the numbers: The average wholesale price of a dozen eggs was $3 Friday, down 8% from $3.27 on March 21, according to U.S. Department of Agriculture data released Friday.

It's down 63% from a record $8.15 in the Feb. 21 report.

The big picture: Retail prices, which typically trail wholesale, are beginning to drift downward as well.

"It was only four weeks ago that we were at the highest price the market had ever seen," Brian Moscogiuri, a global trade strategist at Eggs Unlimited, told Axios. "So it just takes time for those lower prices to be passed along."

Purchasing restrictions and slowing consumer demand also "placed significant downward pressure on the market," Ryan Hojnowski, with price-reporting service Expana, told Axios.

State of play: Inventories are recovering amid a sudden and largely unexplained slowdown in bird flu cases. The Trump administration has also taken steps to boost egg imports to combat higher prices.

Threat level: The U.S. lost more than 12% of its caged egg-laying hens from Jan. 1 to March 21, according to the USDA.

Yes, but: The bird flu outbreak has vacillated in the last three years and could quickly spike again


Experts warn about bird flu in domestic cats: What to know about the virus
Quote:
Nearly a dozen domestic cats in Colorado have gotten the most recent strain of bird flu and officials say only one of the 11 cats survived.

That includes indoor-only and indoor-outdoor cats.

“This is a new and emerging situation we’re learning a lot as we go,” said Dr. Kristy Pabilonia, Executive Director of the Veterinary System Diagnostics Laboratories at Colorado State University.

“More recently we have been detecting highly pathogenic avian influenza virus in domestic cats and seeing more cats more recently than we have in the past,” she said.

Pabilonia says the cases are believed to be linked to raw or undercooked meat, unpasteurized milk, and exposure to and droppings of infected birds.

“I just looked at the number this morning,” said Pabilonia, “In the U.S. so far, there are more than 120 confirmed cases in domestic cats … it’s very concerning. These are people’s pet cats.”

Experts say it’s not the first time they have seen influenza in cats, but they are seeing more cases from this latest outbreak.

“I’ve been here 43 years,” said Dr. Kevin Fitzgerald, Staff veterinarian at the Alameda East Veterinary Hospital. “I’ve seen the different viruses, so I’m never surprised by viruses and what they can do and the extent.”

He says cats that are infected with the avian influenza virus have a variety of symptoms, including fever, lethargy, weakness, loss of appetite, respiratory distress and neurological signs like tremors and seizures.

To prevent your cat from getting the bird flu he says you should start with keeping them indoors.

“Not feeding them raw meat or unpasteurized milk,” said Fitzgerald. “Cleaning up areas outside and keeping our cats away from domestic backyard chickens will be another thing.”

He said that also includes raw pet foods that you can buy at a grocery store.

Experts say being vigilant is important. You want to make sure you monitor your cat’s behavior and what they are doing while outdoors. If your cat experiences any of the symptoms you are urged to seek further help at a veterinary hospital.

This is concerning because more humans come in contact with cats then birds or ducks.


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jimmy m
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29 Mar 2025, 9:27 am

ASPartOfMe wrote:
Egg prices are suddenly plunging as the bird flu begins to wane and imports surge to fill the gap.


Bird flu is seasonal. It correlates with the time birds fly north in the spring and south during the fall in the Northern Hemisphere. So the threat of bird flu comes and goes twice per year.

ASPartOfMe wrote:
Experts warn about bird flu in domestic cats: What to know about the virus[/url]
This is concerning because more humans come in contact with cats then birds or ducks.


Very true, very true. Bird flu is moving closer and closer to humans. They are at our doorstep and in our homes.


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jimmy m
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29 Mar 2025, 10:18 am

The CCP leadership is hiding the explosion of H5N1 in China from public view. But is it visible in one of their close neighbors, India.

India has reported eight outbreaks of highly pathogenic H5N1 bird flu in farms and backyard poultry in Andhra Pradesh.

Source: India reports eight outbreaks of bird flu in Andhra Pradesh

The outbreaks of avian influenza, commonly called bird flu, were all detected in the eastern region of Andhra Pradesh, the Paris-based organisation said in a report. They led to the death or culling of a total 602,000 poultry.

Almost immediately Hong Kong reacted to this news.

Source: Hong Kong suspends import of poultry eggs from Andhra Pradesh, Telangana due bird flu outbreak

In response to fresh outbreaks of highly pathogenic avian influenza (H5N1), commonly known as Bird Flu, in Telangana and Andhra Pradesh, the Centre for Food Safety (CFS) of the Food and Environmental Hygiene Department in Hong Kong has announced an immediate suspension of poultry egg imports from the affected regions.

The decision follows a notification from the World Organisation for Animal Health (WOAH) regarding outbreaks in the Yadadri Bhuvanagiri District of Telangana, as well as the West Godavari, East Godavari, and Krishna Districts of Andhra Pradesh.

One of the more interesting perspectives is Who Controls Hong Kong? And why did they react so quickly, almost at the speed of light.

China pledged to preserve much of what makes Hong Kong unique when the former British colony was handed over in 1997. Beijing said it would give Hong Kong fifty years to keep its capitalist system and enjoy many freedoms not found in mainland Chinese cities.

But China broke its pledge.

But more than halfway through the transition, Beijing has taken increasingly brazen steps to encroach on Hong Kong’s political system and crack down on dissent. In 2020, Beijing imposed a sweeping national security law on Hong Kong. Since then, authorities have arrested dozens of pro-democracy activists, lawmakers, and journalists; curbed voting rights; and limited freedoms of the press and speech. In March 2024, Hong Kong lawmakers passed Article 23, an additional security legislation that further cements China’s rule on the city’s rights and freedom.

Source: Hong Kong’s Freedoms: What China Promised and How It’s Cracking Down

I wonder if China is responsible for the H5N1 pandemic that is slowly creeping across the world. In a similar manner to another pandemic COVID, where they hid the source of the outbreak at a research facility in Wuhan, China from the world. Interesting.


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jimmy m
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Yesterday, 7:13 am

Last night, I thought about the Spanish Flu which broke out in World War I and spread throughout the world killing millions and millions. We now know this disease is called H1N1. H1N1 is very similar to H5N1. They are like twin sisters. So the thought came to me to identify those who experienced this pandemic and may still have some natural immunity. Who lived through this plague?

Purple Death: The Great Flu of 1918

Despite its name, researchers believe the Spanish flu most likely originated in the United States. One of the first recorded cases was on March 11, 1918, at Fort Riley in Kansas. Overcrowding and unsanitary conditions created a fertile breeding ground for the virus. Within one week, 522 men had been admitted to the camp hospital suffering from the same severe influenza. Soon after, the army reported similar outbreaks in Virginia, South Carolina, Georgia, Florida, Alabama and California. Navy ships docked at East Coast ports also reported outbreaks of severe influenza and pneumonia among their crews. The flu seemed to target military personnel and not civilians, so the virus was largely overshadowed by hotter current affairs such as Prohibition, the suffragette movement and the bloody battles in Europe.

By May 1918, influenza began to subside in the United States. But the ordeal was by no means over. Soldiers at Fort Riley, now ready for battle, incubated the virus during their long, cramped voyage to France. Once they hit French shores, the virus exploded, striking the Allied forces and Central Powers with equal force. The Americans fell ill with "three-day fever" or "purple death." The French caught "purulent bronchitis." The Italians suffered "sand fly fever." German hospitals filled with victims of Blitzkatarrh or "Flanders fever."

No matter what they called it, the virus attacked everyone similarly. It started like any other influenza case, with a sore throat, chills and fever. Then came the deadly twist: the virus ravaged its victim's lungs. Sometimes within hours, patients succumbed to complete respiratory failure. Autopsies showed hard, red lungs drenched in fluid. A microscopic look at diseased lung tissue revealed that the alveoli, the lungs' normally air-filled cells, were so full of fluid that victims literally drowned. The slow suffocation began when patients presented with a unique symptom: mahogany spots over their cheekbones. Within hours these patients turned a bluish-black hue indicative of cyanosis, or lack of oxygen. When triaging scores of new patients, nurses often looked at the patients' feet first. Those with black feet were considered beyond help and were carted off to die.

From the battlefields of Europe, the epidemic quickly evolved into a pandemic, as the disease spread north to Norway, east to China, southeast to India and as far south as New Zealand. Even islands weren't safe. Hitching rides on naval ships and carriers, merchant vessels and trains, the virus traveled to the four corners of the earth. By the summer of 1918, it had hit Puerto Rico, the Caribbean, the Philippines and Hawaii. The epidemic wreaked havoc on Puerto Rico but surprisingly barely touched the Panama Canal Zone, the crossroads of the world at the time. The steamship Harold Walker is blamed for bringing Spanish flu to Tampico, Mexico. Within four short months, the virus had rounded the globe and returned once more to U.S. shores.

The second and third waves of Spanish flu slammed the United States in the cold-weather months of 1918. This time civilians were not immune. The country's indigenous people, particularly Native Alaskans, suffered disproportionately. The flu completely wiped out some villages in Alaska, and others lost most of their adult population. Big-city dwellers faired poorly too. New York City buried 33,000 victims. Philadelphia lost nearly 13,000 people in a matter of weeks. Overwhelmed with bodies, many cities soon ran out of coffins and some had to convert streetcars into hearses to keep up with demand.

Most of the deaths caused by H1N1 during the Great War (WWI) were in the Allied forces and Central Powers. They were the countries whose soldiers suffered the most during the Spanish Flu (H1N1) pandemic of 1918 and would hold some immunity within their populations. In my humble opinion, their offspring's would hold some immunity to H1N1 and also to H5N1. That might explain why China is currently experiencing a deadly explosion of H5N1 in the past couple years and why other countries such as the U.S. have a greater immunity. More Americans soldiers died of the Spanish Flu during the war then were killed in actual combat.


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