Bringing back Diana?

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The nub of the issue is you cant "bring a person back". You can only create a biological xerox copy of the person. A younger generation identical twin of that person. One more thing: The clone wont have the person's memories (if thats what you think).

He's arguing Diana did more than them, while you argue Einstein did more than her. In a thread you find pointless.

There is no guarantee that the being who is cloned from Einstein will accomplish much, either.

I think the idea is to clone extinct animals (which is theoretically feasible). Top contender at the moment is the woolly mammoth which the embryo can be inserted in a female African elephant.

But if we clone humans then I can think of other females whom would be great to make "take home" clones

But if we clone humans then I can think of other females whom would be great to make "take home" clones

But thats not even half of it.

There is a certain odd thing that they have discovered when cloning sheep and other non human mammals.

The cells in the cloned creature are somehow already pre aged -to the age of the original animal when they extracted the cells to be cloned from that adult animal.

In human terms- if your 30- and they clone you. Your baby clone would have cells thirty years old. So when you die of old age at say 80, your fifty year old clone person will also die of old age at around the same future time as you- but at age 50 (thirty years younger than you will be at that time) because your cells were 30 when they cloned you.

So your cloned version of Princess Dianne will be biologially already Lady Spencer's adult age when the lady died. Forty, or whatever it was. So your cloned Dianne will also die young, but of old age like forty years sooner than the original princess wouldve died had she lived out her natural life. So she would be a seperate person- but a kind of twin -who wouldnt have quite the same personality as Dianne, and would be destined die young. Not actually "princess Dianne returned to life".

TUESDAY, March 8, 2022 -- Could a reset of your cells bring you the fountain of youth?

Maybe so, if a new study testing the technique in mice ever pans out in humans.

Cells in older people and animals have different patterns of chemicals along their DNA -- called epigenetic markers -- compared to younger people or animals.

In this study, researchers said they were able to partially reset cells to more youthful states in middle-aged and elderly mice by adding a mixture of four reprogramming molecules --- Oct4, Sox2, Klf4 and cMyc, also known as "Yamanaka factors" -- to cells.

This approach was tested on three groups of mice. One group received regular doses between 15 months and 22 months of age, about equivalent to 50-70 years in humans. Another mouse group was treated from 12 through 22 months, about 35-70 years in humans, and a third mouse group was treated for just one month at age 25 months, similar to age 80 in humans.

"What we really wanted to establish was that using this approach for a longer time span is safe," said study co-author Pradeep Reddy, a staff scientist at the Salk Institute in La Jolla, Calif.

"Indeed, we did not see any negative effects on the health, behavior or body weight of these animals," Reddy said in a Salk news release.

The mice that were treated for seven or 10 months showed signs of reversals of aging in locations such as the kidneys and skin, but no such changes were seen in mice treated for just one month.

"We are elated that we can use this approach across the life span to slow down aging in normal animals. The technique is both safe and effective in mice," said study co-author Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory.

"In addition to tackling age-related diseases, this approach may provide the biomedical community with a new tool to restore tissue and organismal health by improving cell function and resilience in different disease situations, such as neurodegenerative diseases," Izpisua Belmonte said in the release.

The researchers now plan to analyze how specific molecules and genes are changed by long-term treatment with the Yamanaka factors, and are also developing new ways of delivering them.

"At the end of the day, we want to bring resilience and function back to older cells so that they are more resistant to stress, injury and disease," Reddy said. "This study shows that, at least in mice, there's a path forward to achieving that."

The findings were published March 7 in the journal Nature Aging.

There trying to clone the wooly mammoth as well

How would a modern-day African elephant cope with a woolly mammoth fetus?

I believe woolly mammoths were considerably larger than present-day elephants.

The appearance of the woolly mammoth is probably the best known of any prehistoric animal due to the many frozen specimens with preserved soft tissue and depictions by contemporary humans in their art. Fully grown males reached shoulder heights between 2.7 and 3.4 m (8.9 and 11.2 ft) and weighed up to 6 tonnes (6.6 short tons). This is almost as large as extant male African elephants, which commonly reach a shoulder height of 3–3.4 m (9.8–11.2 ft), and is less than the size of the earlier mammoth species M. meridionalis and M. trogontherii, and the contemporary M. columbi.

How would a modern-day African elephant cope with a woolly mammoth fetus?

I believe woolly mammoths were considerably larger than present-day elephants.

I suspect their fur makes woolly mammoths look a bit larger than they really are.