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Overcast
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21 Sep 2006, 1:51 am

Are there any drugs which can block or neutralize gluten and casein ?



TheMachine1
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21 Sep 2006, 2:18 am

Overcast wrote:
Are there any drugs which can block or neutralize gluten and casein ?


I would say no. They are just proteins that get broke down into peptides and then
amino-acids like all other protein. A few people may be allergic but there is about
zero science that it will improve ASD or ADHD by avoiding certain proteins. A few
people claim benifts but if you simply lied to people and told them they were on a diet free of Gluten and Casein and equal number would say its a helpfull diet.



psych
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21 Sep 2006, 3:30 am

I read somewhere (on an autistic related page) that L-glutamine may help block adverse reactions to certain foods. Its a supplement (not a drug) and part of the natural diet anyway. Very good for the immune system apparantly - if it doesnt help you can always give it to a erlative with a stomach ulcer - i read somewhere else it cures 90% of stomach ulcers.



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21 Sep 2006, 6:14 am

TheMachine1 wrote:
A few people claim benifts but if you simply lied to people and told them they were on a diet free of Gluten and Casein and equal number would say its a helpfull diet.


i wouldn't be so sure. true there is little in the way of scientific proof, but science has not disproved the link to date either, and there is quite a bit of anecdotal evidence to suggest there may be a link, at least for some people. even the article about it on quackwatch doesn't dismiss the idea out of hand.



TheMachine1
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21 Sep 2006, 6:29 am

peebo wrote:
TheMachine1 wrote:
A few people claim benifts but if you simply lied to people and told them they were on a diet free of Gluten and Casein and equal number would say its a helpfull diet.


i wouldn't be so sure. true there is little in the way of scientific proof, but science has not disproved the link to date either, and there is quite a bit of anecdotal evidence to suggest there may be a link, at least for some people. even the article about it on quackwatch doesn't dismiss the idea out of hand.


I do not dismiss it either . Certain ratio's of amino-acids in the blood can effect the
rate of them crossing the blood brain barrier. Like if you eat a high protein meal
it may be more likely to increase tyrosine and phenylalanine in the brain and that
makes you more stimulated and alert. If you ate a high amount of complex carbohydrates
and low protein that allows more tryptophan to enter the brain making you calm or
sleepy.

So knowing that if a certain amino acid is too high /low or blocked or enhanced
by gluten or Casein can effect some factor in ones mind I will not be surprised at
all. The other poster mentioned Glutamine (an amino-acid) so maybe somebody
has theorised that it may be effected by gluten/casein. I think my real opinion is
its not going to make a major difference in most people.



peebo
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21 Sep 2006, 6:36 am

ah i get your point. incidentally the theory does not posit that an imbalance of amino acids in the brain is the culprit, but that the gut does not suffuciently break down the gluten and casien proteins, and that peptides subsequently pass through the gut lining into the bloodstream and eventually cross the blood brain barrier, causing the problems, hence comparisons are made with leaky gut syndrome.



TheMachine1
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21 Sep 2006, 6:44 am

peebo wrote:
ah i get your point. incidentally the theory does not posit that an imbalance of amino acids in the brain is the culprit, but that the gut does not suffuciently break down the gluten and casien proteins, and that peptides subsequently pass through the gut lining into the bloodstream and eventually cross the blood brain barrier, causing the problems, hence comparisons are made with leaky gut syndrome.


Okay I did read something like peptide chains from casien are structural related to
endorphins (peptides also). So you can get hooked on milk. Maybe some people
leak more of that peptide. I was thinking I would want to be "Null and Void" on
endorphins . Oh for many years I drank about 1/2 gallon (2 liters) of whole milk a day.



peebo
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21 Sep 2006, 7:19 am

yes thats the general idea. the same applies for gluten, and similarly, for years i was actually addicted to grains. would eat 9 or 10 slices of toast on the trot. and would have the most glutenous wholegrain bread i could get my hands on, and eat it with every meal. used to walk 2 miles to buy this dark rye sourdough bread and would easily get through a loaf of it in a day. i actually had withdrawal symptoms when i stopped eating it. :lol:
gluten and i think also casein have been suggested as factors in schizophrenia also

these pages are interesting

http://osiris.sunderland.ac.uk/autism/braithwaite.htm

http://osiris.sunderland.ac.uk/autism/dietinfo.html

this page is humourous, although it does reference all the points it makes http://www.13.waisays.com/zombie.htm



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21 Sep 2006, 7:37 am

If that theory is correct as one of the links mention then the opiate antagonist
Naltrexone could be taken with gluten or casien to block its effects. Answering the
OP question. :)

My nephew and brother are both drug addicts that prefer hydrocodone pills.
I wonder if people with ASD (they do not have ASD but maybe some genes related)
are more or less likely to abuse opiate drugs?