Maybe give them a little time and space for the time being.
And then maybe present the idea that people on the spectrum can be highly successful just like anyone else, with say Jane Austen and Jim Hensen as two famous people who were probably on the Asperger's-Autism Spectrum. Of course anything with art has a lot of luck factors, a lot of external factors, whether someone is on the spectrum or not. But I do like these examples as pointing out that not all of us are math and science only.
The thing that really surprised about jobs is that at least for me "easy" jobs and "hard" jobs are reversed. Kroger was an awful job where the absentee, disengaged managers allowed bullying and in fact blamed the person being bullied. At H&R Block, I was generally appreciated as someone who knew taxes, was good with customers, and had the right kind of patience with the computer system. (job generally only 5 weeks, I did inform my clients of negatives of bank products, fired one year out of four at Block snd this other place for proactively calling clients not approved for loans). So, that means 3 years out of 4 I wasn't fired even though I was a rebel. I felt my loyalty was to my clients and my direct co-workers, and not so much to the company hierarchy.