Because of my sensory issues, I would rather live in an isolated cabin or cottage some distance from any other people, but not so far that I wouldn't be able to get groceries and such without great effort. Maybe a house with a big yard to separate me from neighboring houses would be enough, but I can not yet afford that on my current income which is way way below poverty level. I have had unpleasant exchanges with neighbors, passersby, apartment managers and landlords over noise issues.
I would not like to move to a big city though. The traffic, crowds, etc. would be overwhelming. I prefer living in towns of from ten to twenty thousand population. That's big enough to have decent stores and such, but small enough to not have huge crowds or traffic problems. I think people in towns that size are generally nicer to each other than they are in big cities too.
Smaller towns may be even nicer if people accept you, but of course there are advantages and disadvantages to wherever you choose to live. Big cities might be centers of culture, but I don't go out much and create my own culture for the most part.
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"When you ride over sharps, you get flats!"--The Bicycling Guitarist, May 13, 2008