I was first diagnosed with depression at age 15, then social anxiety at 22, and now only after 10 years, have I been diagnosed with aspergers at age 25.
depression and anxiety disorders are partially hereditary, but you need consistent stress to trigger them.
because our brains "get better" at the neural pathways that are used most often, someone exposed to consistent stress when young is more likely to develop anxiety disorders and depression as an adult.
the normal course of a stress reaction involves an initial stimulus, a stress response from one part of the brain, then a signal to another part of the brain which evaluates the situation "is that a snake or just a stick? is that person a threat or are they just a person?", "am I in danger of ruining everything in my life or did I just mess up once?", and if the evaluation part of the brain says "calm down" it turns the stress hormones off and the anxiety stops.
the brain is amazing about being efficient, though, so if you use certain neural pathways more than others (especially when young) it will reinforce these pathways and your brain gets better at what those pathways do.
if you get many, many stress responses, then to make things more efficient, the evaluation part of the brain eventually gets fewer and fewer signals and you just sit around having a fight-or-fight response to any old stimulus because the part of your brain that stops and asks "do I need to panic over this?" isn't involved anymore.
if you do this for long enough it can burn out receptors for the neurotransmitters that make you happy and relaxed and content, which causes depression. this is why people with depression are often treated with medicines called SSRIs or SNRIs, which keep those chemicals that make you able to be happy or peaceful stay out in the open longer and thus have more of a change for your smaller-than-average number of receptors to receive them and make you something other than depressed. I'm on 20mg of Lexapro per day, which is an SSRI. the vast majority of antidepressants are not "happy pills", they just keep the neuroreceptors you already make from being re-absorbed as quickly, enabling your brain to get the "it's ok" signals that it's supposed to be getting.
another thing that has helped me a lot is mindfulness meditation. because your mind is "plastic" and gets better at things it does repeatedly (like being stressed out), repeatedly suspending your judgement of your thoughts and surroundings and just calming existing can mean that your brain develops more and more of those peaceful awareness pathways just like it reinforced your stress response pathways. there's significant evidence that this kind of meditation can help change the structure of the brain and help people manage and overcome mental illnesses like depression and anxiety.
but yes, people with ASD are probably more likely than the general population to have comorbid anxiety disorders (in fact I think something like 30% of us have social anxiety disorder, which is much higher than average for NTS, and depression is probably higher too but I don't remember) because we often have rather stressful lives, especially before we understand ourselves and can make choices based on our understanding of how our brains are different.
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KADI score: 114/130
Your Aspie score: 139 of 200
Your neurotypical (non-autistic) score: 54 of 200
Conversion Disorder, General/Social Anxiety Disorder, Major Depression
Last edited by Ca2MgFe5Si8O22OH2 on 27 Dec 2012, 4:32 am, edited 3 times in total.