Do you find pain killers dont work?

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I am researching the endocrynology of ASD/Asperger's and finding that some people are reporting that pain medication seems to have little to no effect. There is some data that suggests that this may be true, but nobody has done a survey. I personally have been diagnosed with Asperger's and get zero effect with most types of pain medication except tramadol - where I get really bad side effects and no pain control.

So if you want to answer this question could you indicate if you have formally diagnosed ASD/Asperger's and if you find that pain medication has no effect, little effect, moderate effect, or is very effective. I would prefer that only over 18's answer as data from under 18's cant be included for a survey done in this method as I would need parental pemission to use it.

Also please indicate if you are willing to have the following data used in my survey: Age (over 18), Sex (Male/Female/didnt answer)/effectiveness of the medication/online nickname (nicknames will be omitted from any published data).

Most pain killers work on me, but codeine doesn't. A pharmacist told me I probably lack the enzyme that converts codeine to morphine. I don't think it's autism-related, but I don't know for sure. Go ahead and use me in your survey.

Other pain medications that do work on me are aspirin, ibuprofen, tylenol, acetominophen - basically the typical over the counter anti-inflammatories.

They do not work on me.

I never use pain killers for the simple reason that they don't touch the pain but they make me feel really drowsy.

Not quite related but I'm prescribed klonopin for panic and anxiety attacks and I never feel them or relax after taking one.

For my physical disabilities, I use Tramadol while Lortab does nothing for me. Physicians have told me that different individuals have different reactions to analgesics and opiates.

It didn't work on my broken heart

Paracetamol, ibuprofen and codeine all work fine for me.

Codeine seems to be the only painkiller that works for me.

I have tried every non-prescription analgesic I can find, and all of them have either no effect or a very mild (hardly notable) and very short-lived effect. Local anesthetics I've been given for procedures don't work all that well either.


I was told I have "hypermobility arthralgia".
Basically, I have chronic joint and muscle pain as a result of frequent injuries due to a combination of poor proprioception, muscles activating in the wrong order, and lax joints.
I've read that some people with hypermobility are basically 'immune' to most pain medications.
It really sucks sometimes.


Now, the one thing that did work really well for me is the combination of drugs I was given for general anesthesia for a short procedure once. I believe it was propofol and valium. I was completely pain-free (and anxiety-free) until the effects wore off completely (which was about two days), but it also negatively effected my cognitive abilities in many ways (specifically judgement, awareness, and short-term memory)

Depends on the pain killer...I mean I have never had a severe physical injury really, I agreed to have a muscle biopsy done when I was 18 and had some codeine prescribed for that but that is about it. Aside from that I have taken ibuprophin, tylenol and asprin for monthly female cramps and other minor aches and pains and it can help a little but isn't effective by itself usually have to supplement it with herbal remedies and weed if I have that. I have had vicodin, tramadol and oxycotin(my spelling may be off) but not for pain.... at least not the physical kind and yes I can say they do produce a nice high. Admittedly there are times I am having terrible monthly cramps when I wish I would have saved whatever opiate pill I acquired and got high off of for that time...anyways back to the topic I imagine if I get the high effect they would also be helpful for pain as that to me implies my body responds fairly normally to such drugs.

Well. I can give you a lowdown on what does and doesn't work for me.

Aspen , Tylenol, don't work at all for me.

Ibuprofen works wonders for me. best pain killer out there. No highs, no loliloopyness , just no pain.

More potent stuff. things like hydrocodone and oxycodone give me a wonderful warn and fuzzy feeling without feeling high or loliloopy, and deals with the pain quite well. Oxycontin, O-god that sh!t is nasty, I can't see strait on that stuff. That's one pain killer I do no want to touch, even though it does work on the pain.

Over-the-counter, recipe-free stuff (so, what you get in the supermarket) only works curtesy of the placebo-effect for me; a sugar pill has the same effect.
Stronger, prescription drugs do actually work, but i get a full broadside of side effects (i can ignore the 'possible' from the list of possible effects), so i prefer not to use those.

i have long since took up meditation as a means of pain control; it works wonders and has zero side effects; i can now do so while still roughly functional, so those around me wont realise i'm doing it (except those that know of my habit)