Few physical differences,healthy people vs those with CFS

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Chronic fatigue syndrome (ME/CFS) affects thousands of people in Norway.

Little is understood about the cause of the disease, but research has shown that it can be triggered by infections. Many people develop ME/CFS following a bout of mononucleosis – sometimes called mono or “the kissing disease” – which is a viral infection caused by the Epstein-Barr virus.

But not everyone who gets mono ends up with chronic fatigue syndrome. What separates those who get ME/CFS from those who don’t? Understanding these differences could give us hints about which mechanisms are behind ME/CFS.

The results of a Norwegian study that explored this very question have now been published.
Different interpretations

The results show some small differences in the immune system between people who regain their health and those who develop ME/CFS or other chronic fatigue after mono, but not enough to explain the dramatic disparity in symptoms.